WebCD300a is an inhibitory receptor that is mainly expressed on peripheral eosinophils, mast cells, neutrophils, dendritic cells, macrophages, and some B cells. Cross-linking CD300a by an antibody can induce phosphorylation of tyrosine residues in the cytoplasmic domain, which results in recruitment of phosphatases SHIP, SHP1 and SHP2 and ... WebJun 24, 2014 · Based on these finding we propose that CD300a, a novel PPARβ/δ target gene in macrophages, maintains intestinal immune response. In wild type mice, HFD-derived fatty acids can activate the …
Engulfment signals and the phagocytic machinery for apoptotic cell ...
WebFeb 8, 2016 · To address this issue, we established RAW267.4 mouse macrophage cell lines transfected to stably express CD300a or a control protein (MAIR-II, a member of the CD300 family with high homology to ... WebMar 29, 2024 · CD300a induction by the hypoxic environment represents a mechanism of regulation of monocyte/macrophage pro-inflammatory responses at pathologic sites Title: Identification of CD300a as a new hypoxia-inducible gene and a regulator of CCL20 and VEGF production by human monocytes and macrophages. certify a stand up talk
Identification of CD300a as a new hypoxia-inducible gene …
WebJun 2, 2011 · CD300a belongs to the CD300 family of activating/inhibitory receptors whose genes are clustered in human chromosome 17. 12 CD300a is a type I transmembrane receptor with an IgV-like extracellular domain and a cytoplasmic tail that has 3 classic ITIM motifs 12,13 and is expressed on cells of both lymphoid and myeloid lineages. 12 Its … WebJun 2, 2011 · CD300a down-regulates BCR-mediated activation signals. (A) Purified human B cells (upper panel) or DT40 cells expressing CD300a (lower panel) were loaded with Fluo-4 and Fura-Red. ... In vitro treatment of human monocytes/macrophages with myristoylated recombinant Nef of human immunodeficiency virus type 1 leads to the activation of … Web蛋白酪氨酸磷酸酶C型受體 (英語: Protein tyrosine phosphatase, receptor type, C , 縮寫 : PTPRC )是一個由PTPRC 人類 基因 編碼的 酶 [6] 蛋白酪氨酸磷酸酶C型受體又叫做45號 分化簇 抗原 ,以前曾叫 白細胞常見抗原 (英語: leukocyte common antigen , 縮寫 … certify breakfast video downloads